The Role of Lymphocyte-to-Monocyte Ratio Levels in Diagnosis of Appendicitis in Children

Authors : Kutay Bahadır, Ufuk Ateş, Ergun Ergün, Pari Khalilova, Meltem Koloğlu, Ahmet Çakmak, Gülnur Göllü Bahadır

Pages : 457-461

Doi:10.53394/akd.1328482

View : 52 | Download : 83

Publication Date : 2024-09-19

Article Type : Research Paper

Abstract :Objective: Appendicitis is the most common surgical disease with right lower abdominal pain in pediatric age. This study aimed to investigate the diagnostic value of lymphocyte monocyte ratio (LMR) in appendicitis in children. Methods: A total of 150 patients under the age of 18 who were admitted hospital and given blood samples due to reasons of non-inflammatory conditions and were proved to have appendicitis (non-complicated or complicated) between 2017-2020 were analyzed retrospectively. Patients were classified into three subgroups: Group 1 (healthy children without any inflammation, n=50), Group 2 (non-complicated appendicitis, n=50) and Group 3 (complicated appendicitis, n=50). Results: The median LMR level was significantly lower in the non-complicated and complicated appendicitis groups than in group 1 (p=0,000). The cut-off value of LMR on admission to predict non-complicated appendicitis was 2,98 with a sensitivity of 94% and a specificity of 96% (area under the curve, 0,960, p= 0,000). The cut-off value of LMR on admission to predict complicated appendicitis was 2,15 with a sensitivity of 96% and a specificity of 72% (area under the curve, 0,865, p= 0,000). Conclusion: This study shows that LMR ratio may be helpful with high sensitivity and specificity in diagnosing appendicitis.
Keywords : Apandisit, Çocuk, inflamasyon, lenfosit monosit oranı